Prof. Rachel Martin
Rachel W. Martin is an NMR spectroscopist and structural biologist at the University of California, Irvine, USA. The focus of the Martin lab is the development and application of experimental methodology to investigate protein structure and dynamics. We develop NMR instrumentation for specialized protein experiments as well as characterizing protein structure and function using a variety of biophysical techniques. We are particularly interested in the function and mechanism of proteases, most recently the SARS-CoV-2 main protease (Mpro). We are currently using information gained from molecular modeling and structural biology to design and validate mutation-resistant Mpro inhibitors.