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COVID19-NMR

COVID19-NMR

  • About
    • Mission
    • Participation Guidelines
    • Data Management Plan
    • Research Targets
    • Timeline
  • News
  • Results
    • RNA Results
    • Protein Results
    • Screening RNA
    • Screening Protein
  • Publications
  • Participants
    • Core Team
    • Research Partners
    • Lab Members
    • Corporate Partners
    • Governance Board

Research Targets

The overarching goal of the Project is to promote open science so that we can disseminate important discoveries quickly while also recognizing intellectual contributions from individual partners. Therefore we publish here a list of Protein and RNA targets assigned to the participating groups.

Protein Target Assignment

Parent
protein
Sub-
domain
Coord. PIParticipating
labs (BMRZ)
Participating
labs (external)
PlasmidsExpression/
Preparation
NMR
assignment
Nsp1noSchlundtSchlundt,
Wöhnert
CarlomagnoFrankfurtSchlundtWöhnert
Nsp2HochHochU ConnHochHoch
Nsp3FLSchlundt,
Schwalbe
CERM,
Partras
Frankfurt
Nsp3aSchlundtSchlundtBlackledge FrankfurtSchlundtBlackledge
Nsp3bSchwalbeSchwalbeKnappKnappSchlundt,
Schwalbe
CERM
Nsp3cSpyrouliasSpyrouliasSpyroulias
Nsp3dSchwalbeSchwalbe,
Schlundt
KnappFrankfurtSchlundt,
Schwalbe
Schlundt,
Schwalbe
Nsp3eSchlundtSchlundtSchlundtFrankfurtSchlundtSchlundt
Nsp3YHoch
Nsp3b
SM
Hoch
Nsp3-
3Ecto
Hoch
Nsp4no target
for liquid
state NMR
Nsp5ETH ZurichSchlundt,
Schwalbe
Riek,
Knapp,
Bax,
Karlsson
KnappSchwalbe,
Schlundt
Riek
Nsp6no target
for liquid
state NMR
Nsp7MadisonRienstra,
Kirchdoerfer,
Henzler-Wildmann
UW Madison
Nsp8Madison Rienstra,
Kirchdoerfer,
Henzler-Wildmann
UW Madison
Nsp9SchlundtSchlundtPastoreFrankfurtSchlundtPastore
Nsp10noHengesbachHengesbach,
Schwalbe
FrankfurtHengesbach,
Schwalbe
Schwalbe
Nsp11
Nsp12MadisonRienstra &
Kirchdoerfer
UW Madison
Nsp13SchwalbeKnappKnappSchwalbe
Nsp14HengesbachHengesbach,
Schwalbe
FrankfurtHengesbach,
Schwalbe
Schwalbe
Nsp15
Nsp16HengesbachHengesbach,
Schwalbe
FrankfurtHengesbach,
Schwalbe
Schwalbe
SpikeSchwalbeSchwalbe
RBD
ORF3a
ORF3bWöhnertOhlenschlägerFrankfurtWöhnertOhlenschläger
EnvelopenoGlaubitzSchwalbe,
Glaubitz,
Wöhnert
FrankfurtGlaubitz
Membrane
glyco-
protein
GlaubitzSchwalbe,
Glaubitz
StollFrankfurtGlaubitz
ORF6noSchwalbeFrankfurtSchwalbe
ORF7anoSchwalbeSchwalbeMuhle-GollFrankfurtSchwalbe
ORF7bnoSchwalbeFrankfurtSchwalbe
ORF8noSchwalbe,
Wöhnert
SchwalbeHoch,
Böckmann,
Meier
FrankfurtSchwalbe
Nucleo-
capsid
FLSchlundtBlackledge,
Almeida
NTD (-SR)SchlundtSchlundtBlackledge,
Almeida,
Pierattelli
NTD:
available,
IDPs/SR:
Blackledge,
Pierattelli
DDSchlundtSchlundtSchlundt,
Blackledge
ORF10Schwalbe,
Wöhnert
SchwalbeFrankfurtSchwalbe

RNA Target Assignment

Target RNAParticipating Labs Participating Labs (external)
5_SL1Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
5_SL2+3Fürtig, Schlundt, Schwalbe, Weigand, WöhnertGallego (Valencia)
5_SL4Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
5_SL5Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
5_SL5stemFürtig, Schlundt, Schwalbe, Weigand, Wöhnert
5_SL5AFürtig, Schlundt, Schwalbe, Weigand, WöhnertPetzold (Karolinska)
5_SL5B+CFürtig, Schlundt, Schwalbe, Weigand, WöhnertFrydman (Weizmann)
5_SL6Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
5_SL7Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
5_SL8Fürtig, Schlundt, Schwalbe, Weigand, WöhnertFrydman (Weizmann)
PKFürtig, Schlundt, Schwalbe, Weigand, Wöhnert
3_SL1Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
3_SL2Fürtig, Schlundt, Schwalbe, Weigand, Wöhnert
3_s2mFürtig, Schlundt, Schwalbe, Weigand, Wöhnert
3_HRVFürtig, Schlundt, Schwalbe, Weigand, Wöhnert

Funded by


Goethe Corona Fonds

DFG

Volkswagen Stiftung

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Coordination

Prof. Dr. Harald Schwalbe (Coordinator)
Institut für Organische Chemie und Chemische Biologie
Zentrum für Biomolekulare Magnetische Resonanz

Johann Wolfgang Goethe-Universität
N160-3.13
Max-von-Laue-Strasse 7
D-60438 Frankfurt am Main

Contact us

++49 69 798 29737
schwalbe@nmr.uni-frankfurt.de

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