COVID19-NMR

In March 2020, we initiated the network covid19-nmr and set out the following milestones: In September 2022, we have achieved these milestones and published the following paper. We wish to thank everyone who contributed to our joint efforts. After consultation with the governance board and discussion in the last Covid19-NMR zoom meeting, we think we […]

A new paper from Covid19-NMR participants was recently published in “Science Advances“. RNA-targeted antivirals have been identified using cytotoxicity and SARS-CoV-2 antiviral assays, NMR profiling, virtual ligand screening and small-molecule docking. Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures The current pandemic and likelihood of future coronavirus pandemics, emphasized the urgent need for […]

Our Screening paper “Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome” published in Angewandte Chemie already received quite some attention in several media. Additionally, a recent published article in the national newspaper Süddeutsche Zeitung and local newspaper Frankfurter Neue Presse highlight the outcome of different research groups involved in drug discovery […]